Glassy, plagioclase phenocryst-free, similar to 7-3 Ma, andesitic lavas erupted at the southern end of the Andean Central Volcanic Zone (CVZ) at 27-28 center dot 5 degrees S are argued to contain a component from continental crust that was incorporated into the sub-arc mantle in a major pulse of fore-arc subduction erosion that removed similar to 50 km of fore-arc. The 7-3 Ma amphibole-bearing Pircas Negras (54-64% SiO2) and similar to 7 center dot 7 Ma pyroxene-bearing Dos Hermanos lavas erupted as the frontal arc was displaced some 50 km eastward over a developing bend in the Wadati-Benioff zone at the northern margin of the Chilean-Pampean flat-slab region. Their chemistry differs from that of older Miocene and younger CVZ arc lavas in the region in having more pronounced high field strength element (La/Ta = 40-100; Ba/Ta = 800-2400) and heavy rare earth element (Sm/Yb similar to 4-9) depletions and an extreme adakitic-like character (similar to 600-1400 ppm Sr; Sr/Yb similar to 400-1350). They also differ from older Miocene lavas in having higher Sr-87/Sr-86 and lower Nd-143/Nd-143 at the same wt % SiO2, while still showing trends with increasing wt % SiO2 that are best attributed to contamination in the similar to 65-70 km thick crust. Overall, the trace element and isotopic features of the Pircas Negras lavas are consistent with modeling that attributes differences from older and younger lavas to enrichment of the arc mantle wedge by partial melts of tectonically eroded fore-arc crust, with the modeled eroded component being an outcrop and geophysically constrained mixture of 80-90% Jurassic mafic magmatic rocks and 10-20% silicic Paleozoic crust. An adakitic-type partial melt of this eroded crust generated at > 2 GPa, reacted with mantle peridotite, can explain the high Mg# values (50-61) and Cr (100-350 ppm) and Ni (40-70 ppm) contents in some 5-3 Ma Pircas Negras lavas. Pre-eruption temperatures over 1060 degrees C, calculated from mineral thermometry and the MELTS program, permit these magmas to subsequently melt and react with overlying eclogitic crust. Magma storage in this thick crust then led to amphibole crystallization and suppression of plagioclase fractionation. Quartz and feldspar xenocrysts were acquired from locally pooled mid-crustal magmas and the silicic upper crustal basement during final rapid ascent to the surface. Given a constant arc-trench gap of 300 km over the last 10 Myr, similar to 198 km(3) Myr(-1) km(-1) of fore-arc crust needs to be removed by subduction erosion at 8-3 Ma to account for the material balance of the fore-arc crust.