We prove that for several basic and commonly used rational relations, the intersection problem with regular relations is either undecidable (e. g., for subword or suffix, and some generalizations), or decidable with non-primitive-recursive complexity (e.g., for subsequence and its generalizations). These results are used to rule out many classes of graph logics that freely combine regular and rational relations, as well as to provide the simplest problem related to verifying lossy channel systems that has non-primitive-recursive complexity. We then prove a dichotomy result for logics combining regular conditions on individual paths and rational relations on paths, by showing that the syntactic form of formulae classifies them into either efficiently checkable or undecidable cases. We also give examples of rational relations for which such logics are decidable even without syntactic restrictions.