The Saguinus leucopus is a neotropical primate, endemic and monotypic of Colombia, with few studies reporting its anatomy. The humeral morphology for this species remains unknown and is a key element for the quadruped locomotion of this arboreal animal. The objective of the present study is to describe the gross anatomy and function of the humerus bone in the White-footed tamarin (Saguinus leucopus). The study was based on eight specimens, fixed in 10% formalin and from which we extracted the humeri, describing the main features of the bony prominences, such as muscle attachments and neurovascular pipes. The various anatomical contours of the humerus of Saguinus leucopus exhibit morphological disposition, matching their arboreal quadrupedal and locomotion habits.