We present the results of two Mopra 3-mm spectral line surveys of the lines of sight (LOS) towards the Galactic Centre (GC) molecular complexes Sgr B2 (LOS+0.693) and Sgr A (LOS-0.11). The spectra covered the frequency ranges of similar to 77-93 GHz and similar to 105-113 GHz. We have detected 38 molecular species and 25 isotopologues. The isotopic ratios derived from column density ratios are consistent with the canonical values, indicating that chemical isotopic fractionation and/or selective photodissociation can be considered negligible (<10 per cent) for the GC physical conditions. The derived abundances and rotational temperatures are very similar for both LOSs, indicating very similar chemical and excitation conditions for the molecular gas in the GC. The excitation conditions are also very similar to those found for the nucleus of the starburst galaxy NGC 253. We report for the first time the detection of HCO and HOC+ emission in LOS+0.693. Our comparison of the abundance ratios between CS, HCO, HOC+ and HCO+ found in the two LOSs with those in typical Galactic photodissociation regions (PDRs) and starbursts galaxies does not show any clear trend to distinguish between ultraviolet-and X-ray-induced chemistries. We propose that the CS/HOC+ ratio could be used as a tracer of the PDR components in the molecular clouds in the nuclei of galaxies.