The Lago Teo record shows a conspicuous warm/dry interval between similar to 7500 and 10,000 cal yrs BP followed by a cooling trend and increase in precipitation that has persisted until the present, in agreement with previous studies in the region and interpretations of past southern westerly wind activity at multi-millennial scales. The presence of 26 tephras throughout the record allows examination of the relationship between explosive volcanism and vegetation change under contrasting climatic states of the Holocene. We found consistent statistically significant increases in Tepualia stipularis after tephra deposition over the last 10,000 years, in Eucryphia/Caldcluvia between 7500 and 10,000 cal yrs BP and in Hydrangea over the last 7500 years. Our results indicate a primary role of climate change as driver of long-term vegetation change and as a modulator of vegetation responses to volcanic disturbance at multidecadal and centennial timescales. (C) 2015 Elsevier Ltd. All rights reserved.