This study approaches human encounter and the meaning construction that it unfolds, from a dialogical and micro-process perspective. Considering Valsiner's proposal (2007) a semiotic approach is taken. A Protocol of Analysis is proposed, which describes indicators that regulate the process. Moments of therapeutic dialogue with mothers of sexually abused children were considered in the study. The analysis describes mechanisms that promote the construction, that constrain and enable meanings in dialogue. The participants derived from the impossibility of action to the generation of alternatives in their lives, expressing inter and intra-individual variability of the signification processes. These intersubjective dynamics make possible self and culture joining in a reciprocal process of influences towards stability and change.