Dataciencia

Colección SciELO Chile

Metformin as a prevention and treatment for preeclampsia: effects on soluble fms-like tyrosine kinase 1 and soluble endoglin secretion and endothelial dysfunction

Indexado

WoS	WOS:000371024100015
Scopus	SCOPUS_ID:84959387273

DOI

10.1016/J.AJOG.2015.12.019

Año

2016

Tipo

artículo de investigación

Citas Totales

Autores Afiliación Chile

Instituciones Chile

% Participación
Internacional

Autores
Afiliación Extranjera

Instituciones
Extranjeras

Abstract

CONCLUSION: Metformin reduced soluble fms-like tyrosine kinase 1 and soluble endoglin secretion from primary human tissues, possibly by inhibiting the mitochondrial electron transport chain. The activity of the mitochondrial electron transport chain was increased in preterm preeclamptic placenta. Metformin reduced endothelial dysfunction, enhanced vasodilation in omental arteries, and induced angiogenesis. Metformin has potential to prevent or treat preeclampsia.

Revista

Revista	ISSN
American Journal Of Obstetrics And Gynecology	0002-9378

Métricas Externas

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Disciplinas de Investigación

WOS
Obstetrics & Gynecology

Scopus
Sin Disciplinas

SciELO
Sin Disciplinas

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Publicaciones WoS (Ediciones: ISSHP, ISTP, AHCI, SSCI, SCI), Scopus, SciELO Chile.

Colaboración Institucional

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Autores - Afiliación

Ord.	Autor	Género	Institución - País
1	Brownfoot, Fiona C.	Mujer	Univ Melbourne - Australia University of Melbourne - Australia
2	Hastie, Roxanne	Mujer	Univ Melbourne - Australia University of Melbourne - Australia
3	Hannan, Natalie J.	Mujer	Univ Melbourne - Australia University of Melbourne - Australia
4	Cannon, Ping	-	Univ Melbourne - Australia University of Melbourne - Australia
5	Tuohey, Laura	Mujer	Univ Melbourne - Australia University of Melbourne - Australia
6	Parry, Laura J.	Mujer	Univ Melbourne - Australia University of Melbourne - Australia
7	Senadheera, Sevvandi	-	Univ Melbourne - Australia University of Melbourne - Australia
8	ILLANES-LOPEZ, SEBASTIAN ENRIQUE	Hombre	Universidad de Los Andes, Chile - Chile
9	Kaitu'u-Lino, Tu'uhevaha J.	-	Univ Melbourne - Australia University of Melbourne - Australia
10	Tong, Stephen	Hombre	Univ Melbourne - Australia University of Melbourne - Australia

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Origen de Citas Identificadas

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Citas identificadas: Las citas provienen de documentos incluidos en la base de datos de DATACIENCIA

Citas Identificadas: 0.66 %
Citas No-identificadas: 99.34 %

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Citas identificadas: Las citas provienen de documentos incluidos en la base de datos de DATACIENCIA

Citas Identificadas: 0.66 %
Citas No-identificadas: 99.34 %

Financiamiento

Fuente
National Health and Medical Research Council
NHMRC
Australian Postgraduate Award
National Health and Medical Research Council of Australia (NHMRC)
Arthur Wilson RANZCOG scholarship
CR Roper Research Fellowship
AVANT scholarship

Muestra la fuente de financiamiento declarada en la publicación.

Agradecimientos

Agradecimiento
Supported by The National Health and Medical Research Council of Australia (NHMRC; #1048707, #1046484, #1101871) and an Arthur Wilson RANZCOG scholarship; by an Australian Postgraduate Award and an AVANT scholarship (F.B); by a CR Roper Research Fellowship (N.J.R.); the NHMRC provided salary support (#1050765 [S.T.]; #1062418 [T.K.L.]; #628549 [S.S.]). The funders had no role in study design, data collection, analysis, decision to publish or the preparation of the manuscript.
Supported by The National Health and Medical Research Council of Australia (NHMRC; #1048707 , #1046484 , #1101871 ) and an Arthur Wilson RANZCOG scholarship; by an Australian Postgraduate Award and an AVANT scholarship (F.B); by a CR Roper Research Fellowship (N.J.R.); the NHMRC provided salary support (#1050765 [S.T.]; #1062418 [T.K.L.]; #628549 [S.S.]). The funders had no role in study design, data collection, analysis, decision to publish or the preparation of the manuscript.

Agradecimiento

Supported by The National Health and Medical Research Council of Australia (NHMRC; #1048707, #1046484, #1101871) and an Arthur Wilson RANZCOG scholarship; by an Australian Postgraduate Award and an AVANT scholarship (F.B); by a CR Roper Research Fellowship (N.J.R.); the NHMRC provided salary support (#1050765 [S.T.]; #1062418 [T.K.L.]; #628549 [S.S.]). The funders had no role in study design, data collection, analysis, decision to publish or the preparation of the manuscript.

Supported by The National Health and Medical Research Council of Australia (NHMRC; #1048707 , #1046484 , #1101871 ) and an Arthur Wilson RANZCOG scholarship; by an Australian Postgraduate Award and an AVANT scholarship (F.B); by a CR Roper Research Fellowship (N.J.R.); the NHMRC provided salary support (#1050765 [S.T.]; #1062418 [T.K.L.]; #628549 [S.S.]). The funders had no role in study design, data collection, analysis, decision to publish or the preparation of the manuscript.