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| DOI | 10.1002/BIMJ.201600008 | ||||
| Año | 2017 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
In survival models, some covariates affecting the lifetime could not be observed or measured. These covariates may correspond to environmental or genetic factors and be considered as a random effect related to a frailty of the individuals explaining their survival times. We propose a methodology based on a Birnbaum-Saunders frailty regression model, which can be applied to censored or uncensored data. Maximum-likelihood methods are used to estimate the model parameters and to derive local influence techniques. Diagnostic tools are important in regression to detect anomalies, as departures from error assumptions and presence of outliers and influential cases. Normal curvatures for local influence under different perturbations are computed and two types of residuals are introduced. Two examples with uncensored and censored real-world data illustrate the proposed methodology. Comparison with classical frailty models is carried out in these examples, which shows the superiority of the proposed model.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Leao, Jeremias | Hombre |
Univ Fed Amazonas - Brasil
Univ Fed Sao Carlos - Brasil Universidade Federal do Amazonas - Brasil Universidade Federal de São Carlos - Brasil Universidade Federal de Goiás - Brasil |
| 2 | LEIVA-SANCHEZ, VICTOR ELISEO | Hombre |
Universidad Adolfo Ibáñez - Chile
Pontificia Universidad Católica de Valparaíso - Chile |
| 3 | Saulo, Helton | - |
UNIV FED GOIAS - Brasil
Univ Brasilia - Brasil Universidade Federal de Goiás - Brasil Universidade de Brasília - Brasil |
| 4 | Tomazella, Vera | Mujer |
Univ Fed Sao Carlos - Brasil
Universidade Federal de São Carlos - Brasil Universidade Federal de Goiás - Brasil |
| Fuente |
|---|
| Conselho Nacional de Desenvolvimento Científico e Tecnológico |
| Fondo Nacional de Desarrollo Científico y Tecnológico |
| Fundação de Amparo à Pesquisa do Estado de São Paulo |
| Coordenação de Aperfeiçoamento de Pessoal de Nível Superior |
| CAPES, Brazil |
| Fondecyt, Chile |
| Fundação de Amparo à Pesquisa do Estado de São Paulo |
| Fondo Nacional de Desarrollo Científico, Tecnológico y de Innovación Tecnológica |
| CNPq, Brazil |
| FAPESP, Brazil |
| Fondo Nacional de Desarrollo CientÃfico, Tecnológico y de Innovación Tecnológica |
| Coordenação de Aperfeiçoamento de Pessoal de NÃvel Superior |
| Conselho Nacional de Desenvolvimento CientÃfico e Tecnológico |
| Agradecimiento |
|---|
| The authors thank the Editors and reviewers for their constructive comments on an earlier version of this manuscript that resulted in this improved version. This research work was partially supported by FAPESP, CNPq, and CAPES grants, Brazil, and by FONDECYT 1160868 grant, Chile. |
| The authors thank the Editors and reviewers for their constructive comments on an earlier version of this manuscript that resulted in this improved version. This research work was partially supported by FAPESP, CNPq, and CAPES grants, Brazil, and by FONDECYT 1160868 grant, Chile. |