This article seeks to analyze the disbursement of resources from the Brazilian Constitutional Financing Fund (cff) who celebrated it 25th anniversary in 2014. It argues that the cfc had substantive changes in 2003, when it adopted the dictates of the Basel Accord, gaining a character more focused on market molds, and in 2007 when the National Policy for Regional Development (nprd) came into force. It assesses that the cfc has acted through the development banks managers for the development of productive activities in the North, Northeast and Midwest Brazilian regions contributing to the reduction of latent regional disparities. However, in the midst of the complexity of the regional dimension, especially since the 1980' s, by internal and external constraints, new challenges are placed to promote the development with greater cohesion between the different regions and sub-spaces.