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Multicenter Evaluation of Ceftolozane/Tazobactam for Serious Infections Caused by Carbapenem-Resistant Pseudomonas aeruginosa
| Indexado |
|
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| DOI | 10.1093/CID/CIX014 | ||||
| Año | 2017 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Abstract
A multicenter, retrospective study of patients infected with carbapenem-resistant Pseudomonas aeruginosa who were treated with ceftolozane/tazobactam was performed. Among 35 patients, pneumonia was the most common indication and treatment was successful in 26 (74%). Treatment failure was observed in all cases where isolates demonstrated ceftolozane-tazobactam minimum inhibitory concentrations >= 8 mu g/mL.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | MUNITA-SEPULVEDA, JOSE MANUEL | Hombre |
Univ Texas McGovern Med Sch - Estados Unidos
Universidad del Desarrollo - Chile Center for Antimicrobial Resistance and Microbial Genomics - Estados Unidos Division of Infectious Diseases - Estados Unidos University of Texas System - Estados Unidos |
| 2 | Aitken, Samuel L. | Hombre |
Univ Texas McGovern Med Sch - Estados Unidos
Univ Texas MD Anderson Canc Ctr - Estados Unidos Center for Antimicrobial Resistance and Microbial Genomics - Estados Unidos Division of Pharmacy - Estados Unidos University of Texas System - Estados Unidos |
| 3 | Miller, William R. | Hombre |
Univ Texas McGovern Med Sch - Estados Unidos
Center for Antimicrobial Resistance and Microbial Genomics - Estados Unidos Division of Infectious Diseases - Estados Unidos |
| 4 | Perez, Federico | Hombre |
Case Western Reserve Univ - Estados Unidos
Case Western Reserve University - Estados Unidos |
| 5 | Rosa, Rossana | Mujer |
Jackson Mem Hosp - Estados Unidos
UNIV MIAMI - Estados Unidos Jackson Memorial Hospital - Estados Unidos University of Miami Leonard M. Miller School of Medicine - Estados Unidos |
| 6 | Shimose, Luis A. | Hombre |
Jackson Mem Hosp - Estados Unidos
UNIV MIAMI - Estados Unidos Jackson Memorial Hospital - Estados Unidos University of Miami Leonard M. Miller School of Medicine - Estados Unidos |
| 7 | Lichtenberger, Paola N. | Mujer |
UNIV MIAMI - Estados Unidos
University of Miami Leonard M. Miller School of Medicine - Estados Unidos |
| 8 | Abbo, Lilian M. | Mujer |
Jackson Mem Hosp - Estados Unidos
UNIV MIAMI - Estados Unidos Jackson Memorial Hospital - Estados Unidos University of Miami Leonard M. Miller School of Medicine - Estados Unidos |
| 9 | Jain, Rupali | - |
UNIV WASHINGTON - Estados Unidos
University of Washington, Seattle - Estados Unidos University of Washington - Estados Unidos |
| 10 | Nigo, Masayuki | Hombre |
Univ Texas McGovern Med Sch - Estados Unidos
Division of Infectious Diseases - Estados Unidos |
| 11 | Wanger, Audrey | Mujer |
Univ Texas McGovern Med Sch - Estados Unidos
University of Texas System - Estados Unidos |
| 12 | ARAOS-BRALIC, RAFAEL IGNACIO | Hombre |
Universidad del Desarrollo - Chile
|
| 13 | Tran, Truc T. | Mujer |
Univ Texas McGovern Med Sch - Estados Unidos
Center for Antimicrobial Resistance and Microbial Genomics - Estados Unidos Division of Infectious Diseases - Estados Unidos |
| 14 | Adachi, Javier | Hombre |
Univ Texas MD Anderson Canc Ctr - Estados Unidos
University of Texas MD Anderson Cancer Center - Estados Unidos University of Texas System - Estados Unidos |
| 15 | Rakita, Robert | Hombre |
UNIV WASHINGTON - Estados Unidos
University of Washington, Seattle - Estados Unidos University of Washington - Estados Unidos |
| 16 | Shelburne, Samuel A. | Hombre |
Univ Texas MD Anderson Canc Ctr - Estados Unidos
University of Texas MD Anderson Cancer Center - Estados Unidos University of Texas System - Estados Unidos |
| 17 | Bonomo, Robert A. | Hombre |
Case Western Reserve Univ - Estados Unidos
Case Western Reserve University - Estados Unidos |
| 18 | Arias, Cesar A. | Hombre |
Univ Texas McGovern Med Sch - Estados Unidos
Univ El Bosque - Colombia Center for Antimicrobial Resistance and Microbial Genomics - Estados Unidos Division of Infectious Diseases - Estados Unidos Universidad El Bosque - Colombia |
| Fuente |
|---|
| National Institute of Allergy and Infectious Diseases |
| Chilean Government, Clinica Alemana-Universidad del Desarrollo |
| Cleveland Department of Veterans Affairs Merit Review Program |
| Agradecimiento |
|---|
| This work was supported by the National Institute of Allergy and Infectious Diseases (award numbers R01 AI093749 and R21 AI114961 to C. A. A., R01 AI089891 to S. A. S., R01 AI100560 and R01 AI063517 to R. A. B.); Cleveland Department of Veterans Affairs Merit Review Program (award 1I01BX001974 to R. A. B.); and Chilean Government, Clinica Alemana-Universidad del Desarrollo to J. M. M. |
