We study the physical and dynamical properties of the ionized gas in the prototypical HII galaxy Henize 2-10 using MUSE integral field spectroscopy. The large-scale dynamics are dominated by extended outflowing bubbles that are probably the result of massive gas ejection from the central star forming regions. We derived a mass outflow rate. (M)over dot(out) similar to 0.30 M-circle dot yr(-1), corresponding to mass loading factor eta similar to 0.4, in the range of similar measurements in local luminous infrared galaxies. Such a massive outflow has a total kinetic energy that is sustainable by the stellar winds and supernova remnants expected in the galaxy. We studied the dust extinction, electron density, and ionization conditions all across the galaxy with a classical emission line diagnostic, confirming the extreme nature of the highly star forming knots in the core of the galaxy, which show high density and high ionization parameters. We measured the gas-phase metallicity in the galaxy, taking the strong variation of the ionization parameter into account, and found that the external parts of the galaxy have abundances as low as 12 + log(O = H) similar to 8.3, while the central star forming knots are highly enriched with super solar metallicity. We found no sign of AGN ionization in the galaxy, despite the recent claim of the presence of a supermassive active black hole in the core of He 2-10. We therefore reanalyzed the X-ray data that were used to propose the presence of the AGN, but we concluded that the observed X-ray emission can be better explained with sources of a di ff erent nature, such as a supernova remnant.