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Fat Mass Lowers the Response to Tumor Necrosis Factor-alpha Blockers in Patients with Ankylosing Spondylitis
| Indexado |
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| DOI | 10.3899/JRHEUM.170094 | ||||
| Año | 2017 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Abstract
Conclusion. Higher body fat content at baseline was independently associated with a worse response to treatment with TNF-alpha blockers, measured by ASDAS-CRP and BASDAI change, and might contribute to the lower response rates in female patients. Also, there is a trend toward muscle mass recovery in male patients after treatment.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | IBANEZ-VODNIZZA, SEBASTIAN EDUARDO | Hombre |
Clínica Alemana - Chile
Hospital Padre Hurtado - Chile Hosp Padre Hurtado - Chile |
| 1 | Vodnizza, Sebastián E.Ibáñez | Hombre |
Clínica Alemana de Santiago and Hospital Padre Hurtado - Países Bajos
|
| 2 | Nurmohamed, Michael T. | Hombre |
Reade - Países Bajos
Vrije Univ Amsterdam - Países Bajos Amsterdam UMC - Vrije Universiteit Amsterdam - Países Bajos |
| 3 | Visman, Ingrid M. | Mujer |
Reade - Países Bajos
Amsterdam UMC - Vrije Universiteit Amsterdam - Países Bajos |
| 4 | van denderen, J. C. | - |
Amsterdam Rheumatol & Immunol Ctr - Países Bajos
Amsterdam UMC - Vrije Universiteit Amsterdam - Países Bajos |
| 4 | Christiaan Van Denderen, J. | - |
Amsterdam UMC - Vrije Universiteit Amsterdam - Países Bajos
Amsterdam Rheumatol & Immunol Ctr - Países Bajos |
| 5 | Lems, Willem F. | Hombre |
Reade - Países Bajos
Vrije Univ Amsterdam - Países Bajos Amsterdam UMC - Vrije Universiteit Amsterdam - Países Bajos |
| 6 | Jaime, F. | Mujer |
Pontificia Universidad Católica de Chile - Chile
|
| 7 | van der Horst-Bruinsma, Irene | Mujer |
Vrije Univ Amsterdam - Países Bajos
Amsterdam UMC - Vrije Universiteit Amsterdam - Países Bajos |
| Agradecimiento |
|---|
| From the Amsterdam Rheumatology and Immunology Center, Reade and VU University Medical Center, Amsterdam, the Netherlands; Rheumatology Department, Clínica Alemana de Santiago and Hospital Padre Hurtado, Santiago, Chile. This study was endorsed by an Assessment of Spondyloarthritis international Society Fellowship grant. S.E. Ibáñez Vodnizza, MD, Rheumatology Department, Clínica Alemana de Santiago and Hospital Padre Hurtado; M.T. Nurmohamed, MD, Professor, Amsterdam Rheumatology and Immunology Center, Reade and VU University Medical Center; I.M. Visman, Amsterdam Rheumatology and Immunology Center, Reade; J.C. van Denderen, MD, PhD, Amsterdam Rheumatology and Immunology Center; W.F. Lems, MD, Professor, Amsterdam Rheumatology and Immunology Center, Reade and VU University Medical Center; F. Jaime, MD, Faculty of Medicine, Pontificia Universidad Católica de Chile; I.E. van der Horst-Bruinsma, MD, PhD, Amsterdam Rheumatology and Immunology Center, VU University Medical Center. Address correspondence to Dr. I.E. van der Horst-Bruinsma, Amsterdam Rheumatology and Immunology Center, VU University Medical Center, Room 3A-64, P.O. Box 7057, 1007 MB Amsterdam, the Netherlands. E-mail: ie.vanderhorst@vumc.nl Accepted for publication May 25, 2017. |
