Background and objective: Failed back surgery syndrome (FBSS) is a complex condition characterized by persistent pain after spinal surgery. This study evaluates the effectiveness of radial shockwaves as a co-intervention in combination with conventional physiotherapy to improve pain and functionality in a case of FBSS. Patient and method: A prospective, single-case study was conducted on a 62-year-old patient with pain and severe functional limitation, secondary to FBSS. During 14 sessions, manual therapy and therapeutic exercise were applied, incorporating radial shockwaves from the 5 th session onwards. These were administered in 2 phases: preparation (500 pulses at 1.5 bar and 14 Hz) and treatment (2000 pulses at 5 bar and 5 Hz), distributed bilaterally in the paravertebral musculature (T10-L5), quadratus lumborum, and painful points in the gluteal region. Pain was assessed using the visual analog scale, functionality with the Roland-Morris Questionnaire, and motor control with the modified Timed Up and Go test with accelerometer (inertial measurement unit). Results: A total reduction in pain was observed (visual analog scale: 4.3 to 0) and an 81.25% improvement in functionality (Roland-Morris Questionnaire). The Timed Up and Go test reflected 24.67% less total time, an increase in step cadence, and a significant reduction in the sit-to-stand phase. The greatest changes coincided with the application of radial shockwaves. Conclusion: Radial shockwaves, combined with physiotherapy, may be an effective co-intervention in the rehabilitation of patients with FBSS, optimizing the multimodal management of pain and functionality.