In recent decades, land use changes have experienced a rapid increase due to various environmental, demographic, economic, and sociocultural factors. These changes have led to significant environmental transformations on a global scale, affecting landscape stability and carrying significant implications for global change, habitat loss, biodiversity, ecosystem services, and the productive capacity of ecosystems. The aim of this study is to identify the relationships reported in the scientific literature between land use, biodiversity, and climate change. A dataset of over 20,000 bibliographic records published between 2001 and 2022 was analyzed using bibliometric techniques and specialized software. The results reveal that land use change is one of the main factors associated with global change, disrupting biogeochemical and hydrological cycles. Additionally, it is a leading cause of global biodiversity loss, impacting society's relationship with the environment. The bibliometric analysis demonstrates a rapid increase in scientific publications on this subject in the last 20 years. This reflects the growing interest and concern of the scientific community in understanding the implications of land use change on biodiversity and climate change. In conclusion, this study underscores the importance of comprehending and addressing the effects of land use change on biodiversity and climate change to promote sustainable management practices and the use of appropriate technologies that contribute to understanding phenomena related to global change.