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| DOI | 10.1016/J.EJMP.2017.11.018 | ||||
| Año | 2018 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Purpose: To propose a geometrical margin for definition of the vaginal cuff PTV using only CT images of the full bladder (CTfull) in postoperative cervical cancer patients.& para;& para;Methods: Twenty-nine operated cervical cancer patients underwent volumetric arc therapy with a bladder filling protocol. This study assessed bladder filling using a portable bladder scanner and cone-beam computed tomography (CBCT) during the entire treatment period. The measured bladder volumes with a BladderScan (R) were compared with the delineated volume on CBCT. Titanium clips in the vaginal cuff were analysed to assess geometrical uncertainty and the influence of rectal and bladder volume changes.& para;& para;Results: BladderScan (R) showed good agreement with the delineated volume (R = 0.80). The volume changes in the bladder have a greater influence on the clip displacements than in the rectum. The 95th percentile of uncertainty of the clips in reference to CT(full )in the right-left (RL), the superoinferior (SI), and the anteroposterior (AP) was 0.32, 0.65, and 1.15 cm, respectively. From this result and intra-fractional movements of the vaginal cuff reported by Haripotepornkul, a new geometrical margin was proposed for definition of the vaginal cuff planning target volume (PTV): 0.5, 0.9, and 1.4 cm in the RL, SI, and AP directions, respectively.& para;& para;Conclusions: A new geometrical margin was proposed for definition of the vaginal cuff PTV based on CTfull,which will be needless of empty bladder at the planning CT scan. This method allows patients to reduce the burden and efficient routine CT scans can be improved.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Okamoto, Hiroyuki | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 2 | Murakami, Naoya | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 3 | Claudia Carvajal, C. | - |
Inst Nan Canc - Chile
|
| 3 | CARVAJAL-PAVEZ, CLAUDIA EDITH | Mujer |
Instituto Nacional del Cá ncer - Chile
Inst Nan Canc - Chile |
| 4 | Miura, Yuki | Mujer |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 5 | Wakita, Akihisa | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 6 | Nakamura, Satoshi | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 7 | Nishioka, Shie | - |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 8 | Iijima, Kotaro | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 9 | Inaba, Koji | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 10 | Ito, Yoshinori | Hombre |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 11 | Kato, Tomoyasu | - |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| 12 | Toita, Takafumi | Hombre |
Okinawa Chubu Hosp - Japón
Okinawa Chubu Hospital - Japón |
| 13 | Itami, Jun | - |
Natl Canc Ctr - Japón
National Cancer Center Hospital - Japón |
| Fuente |
|---|
| Japan Society for the Promotion of Science |
| Ministry of Education, Culture, Sports, Science and Technology |
| Japan Agency for Medical Research and Development |
| Japan Agency for Medical Research and Development, AMED |
| National Cancer Center Research and Development Fount |
| Agradecimiento |
|---|
| The authors thank all of the staff involved in radiation therapy in our institution and Mr. Nakamura M in Kyoto university hospital and Mr. Kito S in Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital for technical supports in this study. This research is partially supported by the Japan Agency for Medical Research and Development, AMED (Grant Number 17ck0106305h0001), Grant-in-Aid for Young Scientists (B) from Ministry of Education, Culture, Sports, Science and Technology (Grant Number 26860411), and the National Cancer Center Research and Development Fount (29-E-10). |
| The authors thank all of the staff involved in radiation therapy in our institution and Mr. Nakamura M in Kyoto university hospital and Mr. Kito S in Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital for technical supports in this study. This research is partially supported by the Japan Agency for Medical Research and Development, AMED (Grant Number 17ck0106305h0001 ), Grant-in-Aid for Young Scientists (B) from Ministry of Education, Culture, Sports, Science and Technology (Grant Number 26860411 ), and the National Cancer Center Research and Development Fount ( 29-E-10 ). |