Background: The purpose of the study is to describe burnout in vascular surgeons (VS) in Chile and to determine their associated factors. Methods: Between April and June 2023, accredited Chilean VS were electronically surveyed. The results were analyzed with bivariate analysis and multivariate logistic regression, considering P value <0.05 as significant. Results: Of the 129 accredited VS in Chile, 113 (87.6%) responded, and after excluding 4 retired surgeons and 1 incomplete survey, 108 responses were analyzed representing 83.7% of those invited to participate. Mean age was 49.1 +/- 9.9 years, most were male (85.2%), married/had a partner (83.0%) and had at least 1 child (82.4%). Overall, 62 (57.4%) of respondents had at least 1 symptom of burnout, 25 (23.1%) were at risk for depression, 11 (10.2%) screened positive for depression, and 5 (4.6%) had considered suicide in the last 12 months. In bivariate analysis, factors significantly associated with burnout were younger age, fewer years in practice, recent work-life conflict, degree of fatigue, job satisfaction, with or at risk for depression, sleep problems, lack of vacation time and the specific stressors. In the multivariate analysis, the significant factors were degree of fatigue, degree of resilience, desire for their children to pursue the same career as them, lack of sports or routine exercise, amount of vacation time, and adversities to perform the work at the hospital or clinic. Conclusion: Burnout is highly prevalent in VS in Chile. Risk factors are like those described in the United States and Europe, the most relevant and distinctive being stress generated by work difficulties in hospitals.