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| DOI | 10.1007/S42519-025-00434-6 | ||||
| Año | 2025 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
This paper introduces a novel approach to cure fraction modeling, also known as long-term survival modeling, by focusing on scenarios where a portion of observations is not susceptible to the event of interest. We propose a new defective distribution model based on the Beta distribution, specifically utilizing the defective Gompertz distribution as a foundation, while accounting for censored data and covariates. We demonstrate that the resulting Beta-Gompertz distribution also exhibits defective characteristics, making it particularly suitable for modeling data with cure fractions. To perform inference on the parameters, maximum likelihood estimation is employed, and its asymptotic properties are examined through simulation studies. The proposed methodology is illustrated using a real-world dataset related to the survival time of patients with triple-negative breast cancer from the A.C. Camargo Cancer Center Hospital, located in S & atilde;o Paulo, Brazil.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Tojeiro, Cynthia Arantes Vieira | - |
UNIV FED GOIAS - Brasil
Universidade Federal de Goiás - Brasil |
| 1 | Vieira Tojeiro, Cynthia Arantes | - |
Universidade Federal de Goiás - Brasil
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| 2 | Tomazella, Vera | - |
Univ Fed Sao Carlos - Brasil
Universidade Federal de Goiás - Brasil Universidade Federal de São Carlos - Brasil |
| 3 | Jerez-Lillo, Nixon | - |
Pontificia Universidad Católica de Chile - Chile
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| 4 | Ramos, Pedro Luiz | - |
Pontificia Universidad Católica de Chile - Chile
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| Fuente |
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| National Agency for Research and Development (ANID) |
| Agencia Nacional de Investigación y Desarrollo |
| Agenția Națională pentru Cercetare și Dezvoltare |
| Agradecimiento |
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| Nixon Jerez-Lillo was funded by the National Agency for Research and Development (ANID)/Scholarship Program/Doctorado Nacional/2021-21210981. |
| Nixon Jerez-Lillo was funded by the National Agency for Research and Development (ANID)/Scholarship Program/Doctorado Nacional/2021-21210981. |