The Grand Round is a strategy used in medical education based on the presentation of clinical cases that promotes the learning of practical and professional skills. The School of Medical Technology at the aforementioned university implemented a virtual mode of Grand Round during the pandemic to enable students to develop clinical reasoning, communication skills, and the ability to integrate knowledge. The objective of this article is to characterize the implementation of their strategy in the ophthalmology and bioanalysis specialties. Student interactions observed in the classes are analyzed using a phenomenological approach and a study designed on the basis of an intrinsic case study. The results suggest two main dimensions: first, the involvement of the students, and second, the mediation of the teachers. In conclusion, the Grand Round is an opportunity for active and meaningful learning that requires ensuring conditions for the best interaction of students and to enhance their positive attitude.