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| Indexado |
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| DOI | 10.1002/SIM.70043 | ||||
| Año | 2025 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Kidney cancer, a potentially life-threatening malignancy affecting the kidneys, demands early detection and proactive intervention to enhance prognosis and survival. Advancements in medical and health sciences and the emergence of novel treatments are expected to lead to a favorable response in a subset of patients. This, in turn, is anticipated to enhance overall survival and disease-free survival rates. Cure fraction models have become essential for estimating the proportion of individuals considered cured and free from adverse events. This article presents a novel piecewise power-law cure fraction model with a piecewise decreasing hazard function, deviating from the traditional piecewise constant hazard assumption. By analyzing real medical data, we evaluate various factors to explain the survival of individuals. Consistently, positive outcomes are observed, affirming the significant potential of our approach. Furthermore, we use a local influence analysis to detect potentially influential individuals and perform a postdeletion analysis to analyze their impact on our inferences.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Jerez-Lillo, Nixon | - |
Pontificia Universidad Católica de Chile - Chile
Facultad de Matemáticas - Chile |
| 2 | Tapia, Alejandra | - |
Pontificia Universidad Católica de Chile - Chile
Facultad de Matemáticas - Chile |
| 3 | Lachos, Victor Hugo | - |
Univ Connecticut - Estados Unidos
|
| 3 | Hugo Lachos, Victor | - |
University of Connecticut - Estados Unidos
|
| 4 | Ramos, Pedro Luiz | - |
Pontificia Universidad Católica de Chile - Chile
Facultad de Matemáticas - Chile |
| Fuente |
|---|
| FAPESP |
| Fundação de Amparo à Pesquisa do Estado de São Paulo |
| University of Connecticut |
| Doctorado Nacional |
| Center for Mathematical Sciences |
| Agencia Nacional de Investigación y Desarrollo |
| College of Liberal Arts and Sciences, Arizona State University |
| National Agency for Research and Development |
| Agenția Națională pentru Cercetare și Dezvoltare |
| Center for Mathematical Sciences Applied to Industry (CeMEAI) - FAPESP |
| UConn-CLAS |
| Research Excellence Program at UConn |
| Agradecimiento |
|---|
| The authors would like to thank the editor, associate editor, and anonymous referees for their valuable comments and suggestions, which significantly contributed to the improvement of this article. Additionally, they express gratitude to The Center for Mathematical Sciences Applied to Industry (CeMEAI), funded by FAPESP (grant 2013/07375-0), for providing computational resources. Nixon Jerez-Lillo acknowledges support from the National Agency for Research and Development (ANID) Scholarship Program, Doctorado Nacional, 2021-21210981. Victor Lachos acknowledges partial financial support from UConn-CLAS's Summer Research Funding Initiative 2023 and the Research Excellence Program at UConn. |
| The authors would like to thank the editor, associate editor, and anonymous referees for their valuable comments and suggestions, which significantly contributed to the improvement of this article. Additionally, they express gratitude to The Center for Mathematical Sciences Applied to Industry (CeMEAI), funded by FAPESP (grant 2013/07375\u20100), for providing computational resources. Nixon Jerez\u2010Lillo acknowledges support from the National Agency for Research and Development (ANID) Scholarship Program, Doctorado Nacional, 2021\u201021210981. Victor Lachos acknowledges partial financial support from UConn\u2014CLAS's Summer Research Funding Initiative 2023 and the Research Excellence Program at UConn. |