The COVID-19 pandemic has generated burnout syndrome in nurses. Objective: To identify preventive measures of burnout syndrome in nurses in times of COVID-19 pandemic. Method: Systematic review conducted between August and December 2020, in the databases: PubMed, Scielo, Elsevier, Medline and Cinahl, applying the search engines: burnout syndrome, nurs*, pandemic, covid 19, stress, management, with the Boolean operators AND, OR. We searched for articles published during the year 2020 in English and Spanish. Theses and conference abstracts were excluded. A spreadsheet was used for data collection and analysis. From a total of 626 articles, 17 were selected for analysis. Result: Preventive measures for burnout syndrome in nurses were classified into two categories: 1.- Organizational Strategies, which are subdivided into 9 aspects: 1) mental and physical health, 2) work environment, 3) teamwork, 4) work shift, 5) support groups, 6) online E assistance, 7) training, 8) structure/functioning and 9) health policies. 11. -Personal Stra- rl tegies, focusing on 1) communication, 2) self-care and 3) stress management techniques. p-2 Bo F.) Conclusions: To prevent burnout in nursing in times of pandemic, both organizational and & z E personal measures are fundamental. It is suggested to incorporate programs focused on c5 mental health, to ensure that institutions have the necessary resources to face crises and to ct promote constant communication. In addition, promote the application and deepening of y, these measures in the current and future health crises, for the benefit of the labor welfare P of nurses in the world.