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Chemosensitizing Activity of Histone Deacetylases Inhibitory Cyclic Hydroxamic Acids for Combination Chemotherapy of Lymphatic Leukemia
| Indexado |
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| DOI | 10.2174/1568009617666170623104030 | ||||
| Año | 2018 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Abstract
Conclusion: It was shown that the use of combination of non-toxic doses of cisplatin (cPt) or cyclophosphamide with CHA in most cases result in the appearance of a considerable anti-tumor effect of cytostatics. The highest chemosensitizing activity with respect to leukemia P388 is demonstrated by the CHA derivatives of Valine lc or 2c.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Mishchenko, Denis V. | Hombre |
Russian Acad Sci - Rusia
Moscow Reg State Univ - Rusia Institute of Problems of Chemical Physics of Russian Academy of Sciences - Rusia Moscow Region State University - Rusia |
| 2 | Neganova, Margarita E. | Mujer |
Russian Acad Sci - Rusia
Institute of Physiologically Active Compounds of the Russian Academy of Science - Rusia |
| 3 | Klimanova, Elena N. | Mujer |
Russian Acad Sci - Rusia
Institute of Problems of Chemical Physics of Russian Academy of Sciences - Rusia |
| 4 | Sashenkova, Tatyana E. | Mujer |
Russian Acad Sci - Rusia
Institute of Problems of Chemical Physics of Russian Academy of Sciences - Rusia |
| 5 | Klochkov, Sergey G. | Hombre |
Russian Acad Sci - Rusia
Institute of Physiologically Active Compounds of the Russian Academy of Science - Rusia |
| 6 | Shevtsova, Elena F. | Mujer |
Russian Acad Sci - Rusia
Institute of Physiologically Active Compounds of the Russian Academy of Science - Rusia |
| 7 | Vystorop, Igor V. | Hombre |
Russian Acad Sci - Rusia
Institute of Problems of Chemical Physics of Russian Academy of Sciences - Rusia |
| 8 | Tarasov, Vadim V. | Hombre |
Sechenov First Moscow State Med Univ - Rusia
Sechenov First Moscow State Medical University - Rusia |
| 9 | Chubarev, Vladimir N. | Hombre |
Sechenov First Moscow State Med Univ - Rusia
Sechenov First Moscow State Medical University - Rusia |
| 10 | Samsonova, Anna | Mujer |
Russian Acad Sci - Rusia
Institute of Physiologically Active Compounds of the Russian Academy of Science - Rusia |
| 11 | Ashraf, Ghulam Md | Hombre |
King Abdulaziz Univ - Arabia Saudí
King Abdulaziz University - Arabia Saudí |
| 12 | Barreto, George | Hombre |
Pontificia Univ Javeriana - Colombia
Universidad Autónoma de Chile - Chile Pontificia Universidad Javeriana - Colombia |
| 13 | Yarla, Nagendra S. | - |
GALLY Int Biomed Res Inst Inc - Estados Unidos
GALLY International Biomedical Research Consulting LLC - Estados Unidos |
| 14 | Aliev, Gjumrakch | - |
Russian Acad Sci - Rusia
Pontificia Univ Javeriana - Colombia Universidad Autónoma de Chile - Chile GALLY Int Biomed Res Inst Inc - Estados Unidos Institute of Physiologically Active Compounds of the Russian Academy of Science - Rusia Pontificia Universidad Javeriana - Colombia GALLY International Biomedical Research Consulting LLC - Estados Unidos |
| Fuente |
|---|
| Russian Science Foundation |
| RSF |
| Russell Sage Foundation |
| IPAC |
| scientific projects of IPAC |
| Agradecimiento |
|---|
| This research was supported in part by RSF project #14-23-00160P and the scientific projects of IPAC (topics 48.8. and 48.9). Authors' also very grateful for the animal facilities were provided by Center for preclinical trials of IPAC RAS. |
| This research was supported in part by RSF project #14-23-00160P and the scientific projects of IPAC (topics 48.8. and 48.9). Authors' also very grateful for the animal facilities were provided by Center for preclinical trials of IPAC RAS. |
