Objectives: To develop a strength training protocol based on lactate kinetics in populations with risk factors. Materials and Methods: Through probabilistic sampling, 15 participants (age 35 +/- 53 years, height 1.78 +/- 0.09 m, weight 72 +/- 15 kg, body fat 23 +/- 19%, muscle mass 41 +/- 47%, and maximum oxygen consumption Vo2max 50 +/- 80 ml/kg/min) performed two strength tests in the half squat. The first test was progressive until the anaerobic threshold, from which the average load was obtained and used in the second test, where 15 sets of 15 repetitions were performed with 1-minute rests between each set. Lactate samples were taken during sets 1, 3, 5, 7, 9, 11, 13, and 15. Results: The results of the constant load test describe behavior with little variability between the variables heart rate and lactate. Mean HR: 133.27 +/- 2.36, lactate: 3.01 +/- 0.19. Pearson (R) of 0.719, p < 0.001. The analysis of variance (ANOVA) did not reveal statistically significant differences in group means concerning lactate variables (p < 0.358, F = 1.110) and heart rate (p < 0.221, F = 1.299). Conclusions: These findings highlight the significant relationship between lactate and heart rate during exercise. The estimated effect sizes indicate that these variables have a moderate impact on the observed differences between groups and support the utility of these variables, lactate, as a method.