Introduction: During the last decade neurorehabilitation has begun to pay more attention to the families of people who adquiren neurological damage. This shift seems to respond to a growing number of studies describing significant levels of psychological distress in these families and adviertiendo its impact on the process of rehabilitation. In Chile, unfortunately, we have no studies that explore the emotional state of families in any stage of rehabilitation, this, despite the existence of clinical guidelines that suggest the family approach as a central goal. This lack of information limits both the ability of interventional diagnosis and rehabilitation equipment. The aim of this article is to describe and compare the profile of psychological distress in relatives of people with brain and spinal cord injury rehabilitation in subacute stage. Method: 89 relatives of people with nerve damage (Acquired Brain Injury = 50; Trauma Raquimedular = 39) responded to the General Health Questionnaire-28 as a measure of psychological distress. This instrument consists of four subscales: somatic, anxiety and insomno symptoms, social dysfunction and severe depression. Results: In both populations the total score of the GHQ-28 was observed above the standard population, suggesting clinical levels of psychological distress in 90% of the sample. No differences were observed between the two populations in terms of total score or subscale score, suggesting similar profiles of psychological distress. This profile was characterized by high levels of anxiety and insomnia, followed to a lesser degree of somatic symptoms.