The present analysis explicates the scientometric relationships, in line with entrepreneurial orientation and perseverance, with the purpose of understanding the relationship between entrepreneurial orientation and the construct called grit. The research, in its central purpose, is inserted in the description of bibliometric indicators of scientific development in this field, from the earliest records of the Web of Science database, online, corresponding to January 1, 1975, until December 31, 2023. The reported methodology identified authors, countries, publications, citations, indexed journals, and institutions according to research in the area of entrepreneurial orientation and perseverance in the context of an updated discussion on studies in this field. The results showed sustained evidence regarding a growing development of publications related to the thematic vector, increasing in recent years, and a geographical concentration associated with the United States. Additionally, the lines of research observed in the most influential publications are related to the areas of strategy, performance, and success. Altogether, the main contribution of this research revealed a synthesis of knowledge in the context of a scientometric analysis on entrepreneurial orientation and grit, offering an updated view on research in entrepreneurial orientation and perseverance.