This commentary aims to frame human rights due diligence as a key instrument in risk management of a mining company with a focus on Chile. To this end, we analyse the challenges faced by the industry in a scenario of clean energy development that involves a high demand for minerals such as copper and lithium. It is concluded that human rights due diligence is a requirement for exporting products to certain markets, serves to improve the reputation of companies, and can be an important instrument for risk-management decisions in the mining industry.