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Age-related hearing loss associated with differences in the neural correlates of feature binding in visual working memory
Indexado
WoS WOS:001104117800001
Scopus SCOPUS_ID:85175158959
DOI 10.1016/J.NEUROBIOLAGING.2023.09.016
Año 2023
Tipo artículo de investigación

Citas Totales

Autores Afiliación Chile

Instituciones Chile

% Participación
Internacional

Autores
Afiliación Extranjera

Instituciones
Extranjeras


Abstract



The underlying neural mechanisms underpinning the association between age-related hearing loss (ARHL) and dementia remain unclear. A limitation has been the lack of functional neuroimaging studies in ARHL cohorts to help clarify this relationship. In the present study, we investigated the neural correlates of feature binding in visual working memory with ARHL (controls = 14, mild HL = 21, and moderate or greater HL = 23). Participants completed a visual change detection task assessing feature binding while their neural activity was synchronously recorded via high-density electroencephalography. There was no difference in accuracy scores for ARHL groups compared to controls. There was increased electrophysiological activity in those with ARHL, particularly in components indexing the earlier stages of visual cognitive processing. This activity was more pronounced with more severe ARHL and was associated with maintained feature binding. Source space (sLORETA) analyses indicated greater activity in networks modulated by frontoparietal and temporal regions. Our results demonstrate there may be increased involvement of neurocognitive control networks to maintain lower-order neurocognitive processing disrupted by ARHL.

Revista



Revista ISSN
Neurobiology Of Aging 0197-4580

Métricas Externas



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Disciplinas de Investigación



WOS
Neurosciences
Geriatrics & Gerontology
Scopus
Neurology (Clinical)
Neuroscience (All)
Developmental Biology
Geriatrics And Gerontology
Aging
SciELO
Sin Disciplinas

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Publicaciones WoS (Ediciones: ISSHP, ISTP, AHCI, SSCI, SCI), Scopus, SciELO Chile.

Colaboración Institucional



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Autores - Afiliación



Ord. Autor Género Institución - País
1 Loughrey, David G. - Trinity College Dublin - Irlanda
University of California, San Francisco - Estados Unidos
Univ Dublin - Irlanda
UNIV CALIF SAN FRANCISCO - Estados Unidos
Trinity Coll Dublin - Irlanda
2 Jordan, Catherine - Trinity College Dublin - Irlanda
University of California, San Francisco - Estados Unidos
Univ Dublin - Irlanda
UNIV CALIF SAN FRANCISCO - Estados Unidos
Trinity Coll Dublin - Irlanda
3 LEGAZ, AGUSTINA Mujer Trinity College Dublin - Irlanda
University of California, San Francisco - Estados Unidos
Universidad de San Andrés - Argentina
Universidad Adolfo Ibáñez - Chile
Univ Dublin - Irlanda
UNIV CALIF SAN FRANCISCO - Estados Unidos
Univ San Andres - Argentina
Trinity Coll Dublin - Irlanda
4 Rodriguez, M. Hombre University of Strathclyde - Reino Unido
Univ Strathclyde - Reino Unido
5 Lawlor, Brian A. - Trinity College Dublin - Irlanda
University of California, San Francisco - Estados Unidos
Univ Dublin - Irlanda
UNIV CALIF SAN FRANCISCO - Estados Unidos
Trinity Coll Dublin - Irlanda
6 Reilly, Richard B. - Trinity College Dublin - Irlanda
Univ Dublin - Irlanda
Trinity Coll Dublin - Irlanda

Muestra la afiliación y género (detectado) para los co-autores de la publicación.

Financiamiento



Fuente
Alzheimer's Association
Alzheimer's Society
GBHI
Alzheimer's Society (GBHI)

Muestra la fuente de financiamiento declarada en la publicación.

Agradecimientos



Agradecimiento
David Loughrey is an Atlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI) and is supported with funding from GBHI, Alzheimer’s Association, and Alzheimer’s Society (GBHI ALZ UK-19-591089).
David Loughrey is an Atlantic Fellow for Equity in Brain Health at the Global Brain Health Institute (GBHI) and is supported with funding from GBHI, Alzheimer's Association, and Alzheimer's Society (GBHI ALZ UK -19-591089) .

Muestra la fuente de financiamiento declarada en la publicación.