The nocturnal mesopause region of the Earth's atmosphere radiates chemiluminescent emission from various roto-vibrational bands of hydroxyl (OH), which is therefore a good tracer of the chemistry and dynamics at the emission altitudes. Intensity variations can, for example, be caused by the general circulation, gravity waves, tides, planetary waves, and the solar activity. While the basic OH response to the different dynamical influences has been studied quite frequently, detailed comparisons of the various individual lines are still rare. Such studies can improve our understanding of the OH-related variations as each line shows a different emission profile. We have therefore used about 90,000 spectra of the X-shooter spectrograph of the Very Large Telescope at Cerro Paranal in Chile in order to study 10 years of variations of 298 OH lines. The analysis focuses on climatologies of intensity, solar cycle effect (SCE), and residual variability (especially with respect to time scales of hours and about 2 days) for day of year and local time. For a better understanding of the resulting variability patterns and the line-specific differences, we applied decomposition techniques, studied the variability depending on time scale, and calculated correlations. As a result, the mixing of thermalized and nonthermalized OH level populations clearly influences the amplitude of the variations. Moreover, the local times of the variability features shift depending on the effective line emission height, which can mainly be explained by the propagation of the migrating diurnal tide. This behavior also contributes to remarkable differences in the effective SCE.