Introduction: In Chile, current legislation ensures medical care for trans people in the national public health system. However, this does not apply to all of the national health services. This paper aims to describe the features and relevance of the Attention Protocol implemented by the Talcahuano’s Health Service. A qualitative research study was conducted, and data was collected through semi-structured interviews and focus groups. The information was analyzed with Grounded Theory and a swot Matrix. Development: From the Grounded Theory, two main categories were obtained, which were “Need for despathologization and good treatment” and “Protocol” as such, categories that are articulated through the trans community and the institution. The Protocol’s main features include its pioneering work, par-ticipatory specifications, binding for healthcare personnel and patients, and recognized. From the swot Matrix, it is noted that the main strengths of the Protocol include the dialog between professionals and the trans community, and the openness of the professional team in learning about improving health care for trans people. The main weaknesses include a passive discrimination toward trans people from some health professionals, the lack of certain specific services in the Protocol, and the few hours available for professionals from the Program. Conclusions: The Attention Protocol implemented by the Talcahuano’s Health Service experience is acknowledged as pioneering work in Chile, and it is both valued positively and validated by the national trans community. Hence, the search for a means to replicate this work in other health services is necessary.