This study explores how the patch-hill system works as a strategic model to activate and preserve urban axes located in peripheral areas of the city, mediating between urban and rural areas. The Green Corridor of San Bernardo in Santiago de Chile has been selected as a case study, due to (1) the opportunities present in the peri-urban geography of the city to harmonize the ecological-urban imbalances, (2) it is a set of five hills interconnected by a network of canals in a territory in the process of urban expansion, (3) functioning as a transition area on a metropolitan and communal scale and (4) reducing the erosive impact of the city, and increasing recreational and productive areas and promoting the mobility of the local fauna. The methodology consists of an analysis of the phenomenon of territorial expansion in San Bernardo. Then, the relationship between the project and the hills through which it passes is studied, with emphasis on the agricultural proposal of the Hasbún hill. We conclude that constructing a border that generates relationships between city and hill contributes to the conservation and activation of peripheral urban axes, mediating between the urban and rural, contributing to the consolidation of sustainable cities.