Infectious endocarditis (IE) of the right native valve refers to an infection in the tricuspid or pulmonary valves, whose mortality reaches 6%. The main risk factors of iE are the intravenous drug use, the presence of intra-cardiac or vascular devices, and the underlying presence of cardiac malformations. Its nonspecific symptoms can lead to a late diagnosis with serious consequences, especially considering that the Duke criteria loses sensitivity in the right iE. Although the treatment is aimed at intravenous antimicrobial therapy it can also be surgical depending on the hemodynamic stability, complications, present pathogens and characteristics of the vegetation, among others. The case of a patient with risk factors who was diagnosed with right IE and whose treatment was surgical medical management, will be presented.