Objective: to analyze the psychometric properties of The Revised Sign and Symptom Checklist for HIV (SSC-HIVrev) based on the setting, populations and samples where this instrument has been applied. Method: a bibliographic review conducted in the CINAHL, PubMed and Scielo databases, including articles published between 2001 and 2019 in English, Spanish or Portuguese, using the search concepts "HIV" AND "Signs and symptoms", as relevant in each database. Those articles not using the SSCHIVrev questionnaire or not reporting their psychometric properties were excluded. Results were assessed and analyzed by two researchers; the different psychometric properties were extracted. Results: in total 1.124 records were located, and 16 of these met the selection criteria. After evaluating internal consistency, the Cronbach's Alpha values reported ranged between 0.76 and 0.97. Three studies reported content validity through experts in different settings, one reported construct validity (ability of explaining 73% of the variance by determining eleven factors), and one stated adequate sensitivity to change in the fatigue and depression scales. Conclusion: reliable Cronbach's Alpha values (> 0.70) were found in the different settings where the SSC-HIVrev was applied. There are limited studies about the content validity, construct validity, discriminant validity, and sensitivity to change.