Earthquakes can cause severe damage to structural and non-structural elements of buildings; consequently, they pose high risks to human lives. To mitigate such risks, attention has been paid to enhancing the indoor envi-ronment for increased building safety. Yet little effort has been made to assess a building occupants' evacuation behaviors in response to damage to the indoor environment. This paper addresses this issue with a novel simulation framework that couples human behaviors with changes to the indoor building environment during post-earthquake evacuation. In particular, we present a building information modelling (BIM)-based prototype that simulates seismic damage to the non-structural indoor elements and visualizes its impacts on evacuation using a color-coded heat map. The simulated damage is then used as input to an agent-based model for post -earthquake evacuation. Using a probabilistic method to assess the non-structural elements' damage states, we are able to evaluate the impact of indoor damage on the evacuation process. We performed a trial of our pro-totype for a hypothetical earthquake in an educational building. The results revealed how the average evacuation time would increase as the earthquake intensity increases (from 38.6 s for the no-damage scenario to 122.9 for the highest-damage scenario). The proposed prototype has the potential to be joined with other tools, such as finite-element-based simulation, to incorporate structural analysis as well. Planners and designers can explicitly use our model's output to analyze the post-earthquake evacuation with the indoor non-structural damage to assess different building design geometries that increase the chances of a suitable evacuation process.