This article analyzes the common theological and spiritual places of two works and processes that were relevant in the 16th century in Spain: Third Spiritual Alphabet (1527) by Francisco de Osuna and the Spiritual Exercises of Saint Ignatius of Loyola. Both represent two seemingly opposite central schools in the history of spirituality-the Franciscan Mysticism and the Ignatian Spirituality. However, through intertextual analysis and after offering a descriptive framework of the context, we study a series of relevant confluences for Theology and Spirituality: 1) The immediate Experience of God; 2) The recollection or non-fragmentation of the understanding in the transformative process in God; and 3) Light or Lucidity as a gift of spiritual discernment and adherence to Christ, visible through the gift of tears.