The following article focuses on the figure of commissioner Tomas Perez, nephew of Bishop Juan Perez de Espinosa, with the aim of detailing the political and social network they configured, as well as the disputes and oppositions they had with other networks of political, social, and family influences in the first half of the 17th century in the diocese of Santiago. This period was, perhaps, the one with the greatest inquisitorial activity in the Viceroyalty of Peru, and which corresponds, in turn, to the moment in which the Government of Chile "is in the world", which implied the translation of knowledge and ideals in vogue to the particular Chilean reality, which entailed, on the one hand, global linkage and synchrony, and on the other, the local translation and diachrony of the Spanish Monarchian vision.