In the framework of the low-energy effective field theory of the Standard Model extended with heavy neutral leptons (HNLs), we calculate the production rates of HNLs from meson decays triggered by dimension-six operators. We consider both lepton-number-conserving and lepton-number-violating four-fermion operators involving either a pair of HNLs or a single HNL. Assuming that HNLs are long-lived, we perform simulations and investigate the reach of the proposed far detectors at the high-luminosity LHC to (i) active-heavy neutrino mixing and (ii) the Wilson coefficients associated with the effective operators, for HNL masses below the mass of the B-meson. We further convert the latter to the associated new-physics scales. Our results show that scales in excess of hundreds of TeV and the active-heavy mixing squared as small as 10−15 can be probed by these experiments.