The transition from the 20th- to 21st-century education is a vital and complex process for Higher Education Institutions (HEIs). It requires constant updating of their strategic plan, ensuring all internal competencies necessary for improving and adapting their teaching and learning processes are in place. This paper presents the design and evaluation of the PROF-XXI tool, a web-based dashboard designed to help HEIs make such transformation sustainable and support their Teaching and Learning Centres (TLCs) in decision making about teaching and learning strategies. The tool is based on the PROF-XXI competency framework, which offers a holistic perspective on the competencies that TLCs should develop to support deep and sustainable transformations. Through a structured interview carried out with 17 participants from 8 HEIs, this study evaluates the extent to which the proposed tool assists users with identifying the required competencies and monitoring their evolution. The results show the value of the tool to improve and monitor the institutions' innovative teaching and learning competencies, the most appropriate indicators for this purpose and suggestions on adaptations to the existing features of the tool.