This article reflects upon the constitutional politics of the Anthropocene within the Chilean constituent process. In that regard, it describes the emergence, consolidation and deficiencies of environmental constitutionalism and explains the elements of a new epistemic framework for the constitutionalism of the Anthropocene. After some thoughts on the constitutional regulation for the Anthropocene, it proposes a general clause that allows the Chilean State to address the challenges that the Anthropocene raises upon constitutional law.