The aim of the study was to compare the prediction of the VO(2)max in breast cancer survivors and a control group (CG) of women without a history of cancer. It is a case-control study. Seventeen women in the breast cancer survivors (49.4 +/- 8.9 years, body mass index [BMI] of 27.8 +/- 2.7 kg.m(-2)) and 17 in the CG (47.9 +/- 7.4 years, BMI of 26.2 +/- 4.4 kg.m(-2)) were evaluated. The six-minute walk test (SMWT) was evaluated with a heart rate monitor, digital blood pressure monitor, pulse oximeter and the Borg scale. The VO2max it was estimated with an equation that considered the distance traveled, body weight and age. The survivors group walked 34.8 meters more than the CG (p = .15). In addition, group showed a trend (p = .05), with a moderate effect size (d = .76), towards an increase in VO(2)max (1.74 +/- .26 L.min(-1)) compared to the CG (1.56 +/- .21 L.min(-1)). There were no differences between the groups for the variables of heart rate, blood pressure and perceived exertion during the test (p > .05). The participants who covered the longest distance had a better chance of a VO(2)max higher (odds ratio = 12.7; p = .002). There were differences in the VO(2)max between groups, this physical fitness should be considered for post-operated treatment and monitoring.