Muestra métricas de impacto externas asociadas a la publicación. Para mayor detalle:
| Indexado |
|
||||
| DOI | 10.1016/J.RADMEAS.2018.07.004 | ||||
| Año | 2018 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
The use of additives in polymer gel dosimeters to enhance their sensitivity or to improve their performance is of great importance for their application in radiomedicine. Inorganic salts have been used as additives with this purpose; however, their presence in the dosimeters induce severe modifications in their mechanical properties and consequently in their capabilities to maintain a stable dose distribution with time. Most studies in this area conclude in the need to use chemical modifications of the species responsible for the mechanical properties of the dosimeters, which in most cases is a gelatin matrix. In this study, a covalent crosslinking of the gelatin matrix of PAGAT dosimeters doped with different inorganic salts, namely MgCl2, CaCl2 and MnCl2 has been carried out. The mechanical properties, X-ray sensitivity and dose distribution stability in these materials were compared to those of PAGAT. The results indicated a compromise between the crosslinking of the gelatin structure and the sensitivity of the dosimetric material. Therefore, the proper selection of the degree of crosslinking and the inorganic salt concentration must be considered. An enhanced dosimeter was obtained by adding MgCl2 with a 1M concentration and by crosslinking the gelatin matrix with glutaraldehyde at a 0.08% w/v concentration. This material presented a 75% enhanced sensitivity relative to PAGAT and similar temporal stability and spatial stability in 2D dose distributions.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Chacon Obando, D. | Hombre |
UNIV NACL CORDOBA - Argentina
UNIV NACL - Costa Rica Universidad Nacional de Córdoba - Argentina Universidad Nacional de Costa Rica - Costa Rica Universidad Nacional - Costa Rica |
| 2 | Strumia, Miriam | Mujer |
UNIV NACL CORDOBA - Argentina
Comision Nacional de Investigacion Cientifica y Tecnologica - Argentina Universidad Nacional de Córdoba - Argentina Consejo Nacional de Investigaciones Científicas y Técnicas - Argentina Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Argentina |
| 3 | Valente, Mauro | - |
UNIV NACL CORDOBA - Argentina
Comision Nacional de Investigacion Cientifica y Tecnologica - Argentina Universidad de La Frontera - Chile |
| 4 | Mattea, F. | Hombre |
UNIV NACL CORDOBA - Argentina
Comision Nacional de Investigacion Cientifica y Tecnologica - Argentina Universidad Nacional de Córdoba - Argentina Consejo Nacional de Investigaciones Científicas y Técnicas - Argentina Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Argentina |
| Fuente |
|---|
| Consejo Nacional de Investigaciones Científicas y Técnicas |
| CONICET |
| Universidad de La Frontera |
| DIUFRO |
| Universidad Nacional |
| SECyT-UNC |
| Consejo Nacional de Investigaciones CientÃficas y Técnicas |
| Universidad Nacional (UNA), Heredia, Costa Rica |
| Universidad de La Frontera by DIUFRO |
| Agradecimiento |
|---|
| This study was partially financed by CONICET by means of the Project ESPORA IePIP 112-20130100658CO, PIP 112-0.20110101029 and SeCyT-UNC by means of DOSCOM I project and INSPIRATE I program. This project was also partially supported by Universidad de La Frontera by DIUFRO DI6008-16 and DI1003-17 projects. The authors would also like to thank to Universidad Nacional (UNA), Heredia, Costa Rica for the financial support (JB-C 0612-2014) of the PhD studies of D. Chacon. |
| This study was partially financed by CONICET by means of the Project ESPORA IePIP 112-20130100658CO , PIP 112–0.20110101029 and SeCyT-UNC by means of DOSCOM I project and INSPIRATE I program. This project was also partially supported by Universidad de La Frontera by DIUFRO DI6008-16 and DI1003-17 projects. The authors would also like to thank to Universidad Nacional (UNA), Heredia, Costa Rica for the financial support ( JB-C 0612–2014 ) of the PhD studies of D. Chacón. |