The Sao Francisco River basin is one of the largest in the Brazilian territory. This basin has enormous economic, social and cultural importance for the country. Its water is used for human and animal supply, irrigation and energy production. This basin is located in an area with different climatic characteristics (humid and semiarid) and studies related to precipitation are very important in this region. In this scenario, the objective of this investigation is to present an assessment of rainfall estimated through the Integrated Multi-SatellitE Retrievals for Global Precipitation Measurement (IMERG) product compared with rain gauges over the Sao Francisco river basin in Brazil. For that, a period from of 20 years and 18 surface weather stations were used to evaluate the product. Based on different evaluation techniques, the study found that the IMERG is appropriate to represent precipitation over the basin. According to the results, the performance of the IMERG product depends on the location where the rain occurs. The bias ranged from -1.67 to 0.34 mm, the RMSE ranged from 5.36 to 10.36 mm and the values of the correlation coefficients between the daily data from the IMERG and rain gauge ranged from 0.28 to 0.61. The results obtained by Student t-test, density curves and regression analysis, in general, show that the IMERG is able to satisfactorily represent rain gauge data. The exception is the eastern portion of the basin, where the product, on average, underestimates the precipitation (p-value < 0.05) and presents the worst statistical metrics.