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EBiSC best practice: How to ensure optimal generation, qualification, and distribution of iPSC lines
| Indexado |
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| DOI | 10.1016/J.STEMCR.2021.07.009 | ||||
| Año | 2021 | ||||
| Tipo | artículo de investigación |
Citas Totales
Autores Afiliación Chile
Instituciones Chile
% Participación
Internacional
Autores
Afiliación Extranjera
Instituciones
Extranjeras
Abstract
Disease-relevant human induced pluripotent stem cells (iPSCs) are generated worldwide for research purposes; however, without robust and practical ethical, legal, and quality standards, there is a high risk that their true potential will not be realized. Best practices for tissue procurement, iPSC reprogramming, day-to-day cultivation, quality control, and data management aligned with an ethical and legal framework must be included into daily operations to ensure their promise is maximized. Here we discuss key learning experiences from 7 years of operating the European Bank for induced Pluripotent Stem Cells (EBiSC) and recommend how to incorporate solutions into a daily management framework.
| Ord. | Autor | Género | Institución - País |
|---|---|---|---|
| 1 | Steeg, Rachel | Mujer |
Fraunhofer UK Res Ltd - Reino Unido
Fraunhofer UK Research Ltd - Reino Unido |
| 2 | Mueller, Sabine C. | Mujer |
Fraunhofer Inst Biomed Engn IBMT - Alemania
Fraunhofer Institute for Biomedical Engineering IBMT - Alemania |
| 3 | Mah, Nancy | Mujer |
Fraunhofer Inst Biomed Engn IBMT - Alemania
Fraunhofer Institute for Biomedical Engineering IBMT - Alemania |
| 4 | Holst, Bjorn | Hombre |
Bioneer AS - Dinamarca
|
| 5 | Cabrera-Socorro, Alfredo | Hombre |
Janssen Res & Dev - Bélgica
Janssen Research & Development - Bélgica |
| 6 | Stacey, Glyn N. | Mujer |
Int Stem Cell Banking Initiat - Reino Unido
CASSACA - China International Stem Cell Banking Initiative - Reino Unido Institute of Zoology Chinese Academy of Sciences - China Chinese Academy of Sciences - China |
| 7 | De Sousa, Paul A. | Hombre |
UNIV EDINBURGH - Reino Unido
Edinburgh Medical School - Reino Unido |
| 8 | Courtney, Aidan | Hombre |
KWWK Ltd - Reino Unido
|
| 9 | Zimmermann, Heiko | Hombre |
Fraunhofer Inst Biomed Engn IBMT - Alemania
Saarland Univ - Alemania Universidad Católica del Norte - Chile Fraunhofer Institute for Biomedical Engineering IBMT - Alemania Universität des Saarlandes - Alemania |
| Fuente |
|---|
| Horizon 2020 Framework Programme |
| European Federation of Pharmaceutical Industries and Associations |
| Innovative Medicines Initiative |
| EFPIA |
| Innovative Medicines Initiative 2 Joint Undertaking (JU) |
| EU's Horizon 2020 research and innovation program |
| EU's Horizon 2020 |
| Agradecimiento |
|---|
| Many thanks to Dr. Timothy E. Allsopp, Dr. Andreas Ebneth, and Kevin Bruce for their broad input into development of EBiSC processes. Thank you to Dr. Ralf Kettenhofen for support with formalizing Figures 1 and 2. Figures were created with BioRender.com. EBiSC2 has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement no. 821362. The JU receives support from the EU's Horizon 2020 research and innovation program and EFPIA. |
| Many thanks to Dr. Timothy E. Allsopp, Dr. Andreas Ebneth, and Kevin Bruce for their broad input into development of EBiSC processes. Thank you to Dr. Ralf Kettenhofen for support with formalizing Figures 1 and 2 . Figures were created with BioRender.com . EBiSC2 has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement no. 821362 . The JU receives support from the EU's Horizon 2020 research and innovation program and EFPIA . |
