Since health care delivery in Chile was comprehensively reformed in 2005, treating schizophrenia for its populace has been guaranteed, regardless of individuals' type of health insurance coverage. The implementation of this national schizophrenia treatment program has facilitated timely access to care for Chileans with a first episode of schizophrenia, particularly for publicly insured individuals. Although this reform has benefited 98% of the population, significant challenges remain. These include the transition to new evidence-based interventions, such as coordinated specialty care with multielement interventions, and the development of an information system that permits monitoring and improvement of quality of care and treatment outcomes.