In the present investigation we evaluate the effectiveness of a group therapy program for self-care with cognitive-behavioral orientation, designed to be used on clinical psychologists with high levels of secondary traumatic stress. The object of this group therapy program is to increase the frequency of emissions of self-care behaviors and decrease the levels of secondary traumatic stress in psychologists. By a quasi-experimental design we evaluate the group therapy program effects. The results indicate that, after 5 sessions that lasts the group therapy program, the psychologists that participated in it (n = 9) increased significantly their self-care behaviors and decreased significantly their secondary traumatic stress levels. Instead, the psychologists that didn't participate in the group therapy program (n = 12) didn't show variation on self-care frequency and they increased secondary traumatic stress. These results are conclusive that the group therapy program is effective and it represents an alternative to prevent and treat work related burnout in clinical psychologists.