We report herein the synthesis, crystallographic analysis and a study of the non-covalent interactions observed in the new 4'-substituted terpyridine-based derivative bis[4'-(isoquinolin-2-ium-4-yl)-4,2':6',4 ''-terpyridine-1,1 ''-diium] tris-[tetrachloridozincate (II)], (C24H19N4)(2)[ZnCl4](3) or (44TPH(3))(2)[ZnCl4](3), where (44TPH(3))(3+) is the triply protonated cation 4'-(isoquinolinium-4-yl)-4,2':6',4 '' terpyridinium. The compound is similar in its formulation to the recently reported 2,2';:6',2 '' terpyridinium analogue {bis[4'-(isoquinolin-2-ium-4-yl)-2,2':6',2 ''-terpyridine-1,1 ''-diium] tris[tetrachloridozincate(II)] monohydrate; Granifo et al. (2017). Acta Cryst. C73, 1121-1130}, although rather different and much simpler in its structural features, mainly in the number and type of non-covalent interactions present, as well as in the supramolecular structure they define.