In recent years, it has been observed that several banks around the world have decided not to initiate, or terminate, pre-existing commercial relationships with clients considered to be of higher risk regarding money laundering and/or terrorist financing (ML/TF). The study of this phenomenon, known as de-risking, is the main objective of this work. The article reviews the context in which this practice has been originated, examines the main causes and repercussions attributed to it in relation to the prevention of ML/TF, as well as those categories of clients affected by it, both in Chile and abroad, and identifies some possible ways of solving this phenomenon.