Accelerograms of large subduction earthquakes are characterized by their long duration of some minutes leading in some cases to absolute response spectra with two clear peaks. This particular feature is associated with the separated participation effect of source from soil response in different stages of energy release from the dominating asperities of subducted plate. In this paper, 2PRS obtained from the accelerograms of 2010 Chile, 2015 Nepal, 2016 Ecuador, and 2017 Mexico earthquakes are analyzed, showing 2PRS for large subduction earthquakes are the rule for soft soils. In addition, it is demonstrated that period of soil peak coincides with the one estimated by Nakamura method. The actual importance of 2PRS for earthquake engineering is that source peak affects houses or middle-rise buildings and soil peak affects high-rise buildings or base-isolated buildings. Therefore, design response spectra considered in seismic codes for soft soils should be modified in future in order to consider both effects.