A back-arc setting for the Lower Cretaceous volcanic rocks in the Andean Cordillera of Central Chile (31-34°S), previously proposed on paleogeographic grounds, is consistent with their geochemical features. The rocks are basic to intermediate lavas, predominantly basaltic andesites, of low initial 87Sr/86S ratio (0.7031-0.7039). They are characterized by relatively high contents of Ta, Nb, Zr and Hf compared with Y and Yb, consistent with an enriched mantle source, or a low degree of partial melting, or both. High contents of alkalis and Th relative to HFS elements are interpreted as a crustal contribution. The Ba/La, Ba/Nb and V/Ti ratios are lower than in coeval island arc lavas in the Coastal Cordillera. The Ce/ Yb, Ce/Sm, Th/Yb and initial 87Sr/86Sr ratios show a northward decrease within the studied sector consistent with a thinner crust in the north during the Early Cretaceous, contrary to the present situation.