The political agenda in an electoral context has multiple supports on which to be built: besides traditional media, social networks have adopted a leading role in the strategies of the parties. The current research analyzes for 28 days the official Twitter accounts of the two main presidential candidates in Argentina, Peru, Ecuador, Honduras and Chile, during the elections held in Latin America in the 2015-2017 period. The thematic agendas of the candidates and the countries are exposed through the use of a quantitative methodology, content analysis and the use of tools such as Python Twint, NVivo and SPSS, whilst Spearnnan's Rho coefficient was applied for the extraction of correlations. In conclusion, the absence of a particular digital agenda in Latin America has been inferred, within a coherent thematic behavior through the left-right axis and the national politics.