Grid Computing is a relatively new, distributed computing technology, based on sharing different types of computational resources, located in various geographic locations. Usability evaluation for Grid Computing applications brings new challenges. There is a need for new usability evaluation methods or at least for the use of traditional evaluations in novel ways. A set of specific usability heuristics was defined and validated. A usability checklist to be used when applying Grid Computing heuristics is also proposed. © 2011 IEEE.