This paper presents results of three alternative hydrodynamic set-ups of the TankCell 300 flotation cell compared to two TankCell 160 machines. Variables were speed and use of an additional impeller (FlowBooster). Results indicated that the use of the FlowBooster seemed to produce better metallurgy. Results in each hydrodynamic set-up were analyzed in terms of global recovery and grade, recovery-by-size and grade-by-size for both Copper and Molybdenum. Gas dispersion was also examined. Finally, different residence times were used in the 300 m 3 cell with and without the additional impeller. This test indicates that the kinetic rate of flotation may be higher when using the FlowBooster. In addition, Computational Fluid Dynamics has progressed by including bubble pressure for modeling bubble-particle interactions. Bubble pressure is a result of ambient flow field, and it can be shown that a certain range is beneficial for particle collection. This "bubble over-pressure" is used to map the collision-attachment regimes under different conditions. Analysis indicates that the setup with FlowBooster seems to increase the number of bubbles with pressure in the optimal range.